Design, Fabrication and Characterization of Antiemetic Transdermal Patches Loaded Dissolvable Microneedles
نویسندگان
چکیده
Various non-invasive administration has been recently coming as an excellent alternative to conventional administrative mechanism. A transdermal drug delivery system with polymeric microneedles presents the most attractive method among all these because of its low rejection rate, higher bioavailability, super convenience, ease and termination, biodegradable persistence in skin care industry. However, physiochemical properties made them protect inner environment this mechanism play barrier for TDDS, hence bio dissolvable biocompatible microneedle can be choice. In research, we fabricated characterized different proportions polymer blend solution effective improved bioavailability Ondansetron HCl. We TDDS on progression mechanically strength determination by folding endurance, flatness study, gelatin sheets beds penetration application, percentage content releasement under FT-IR studied microscopic images shape size microneedle. addition, desired physical had established high efficiency inherent which expected find a broad range application fields.
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ژورنال
عنوان ژورنال: International journal of innovative technology and exploring engineering
سال: 2023
ISSN: ['2278-3075']
DOI: https://doi.org/10.35940/ijitee.e9493.0412523